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主营:主营:ELISA、抗体、试剂、试剂盒、细胞培养、转染、MHC四聚体、蛋白质和肽、四聚体和单体等
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当前位置: 首页 > 产品中心 > Specialty_ELISA_kits > MBL(CycLex&CircuLex)/CircuLex小鼠/大鼠PCSK9 ELISA试剂盒/CY-8078/96分析
商品详细MBL(CycLex&CircuLex)/CircuLex小鼠/大鼠PCSK9 ELISA试剂盒/CY-8078/96分析
MBL(CycLex&CircuLex)/CircuLex小鼠/大鼠PCSK9 ELISA试剂盒/CY-8078/96分析
MBL(CycLex&CircuLex)/CircuLex小鼠/大鼠PCSK9 ELISA试剂盒/CY-8078/96分析
商品编号: CY-8078
品牌: CycLex & CircuLex
市场价: ¥9083.15
美元价: 6987.04
产地: 美国(厂家直采)
公司:
产品分类: 特色ELISA试剂盒
公司分类: Specialty_ELISA_kits
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
ComponentsMicroplate,WashBuffer,DilutionBuffer,MousePCSK9Standard,HRPconjugatedDetectionAntibody,SubstrateReagent,StopSolution
IntendeduseThisKitisusedforthequantitativemeasurementofMouseandRatPCSK9inserum,plasma,cellculturemediumandotherBIOLOGicalmedia.
Storagetemp.4°CManufacturerMBL
SampleSerum,Plasma,Cellculturemedium,Otherbiologicalmedia
Measurementrange0.094~6ng/mL
Sensitivity38.1pg/mL~
Citations
  1. ChenXWetal.SEC24AdeficiencylowersplasmacholesterolthroughreducedPCSK9secretion.Elife.2,e00444(2013)(PMID:23580231)
  1. CarrierBetal.Alpha-lipoicacidreducesLDL-particlenumberandPCSK9concentrationsinhigh-fatfedobeseZuckerrats.PLoSOne.9,e90863(2014)(PMID:24595397)
  1. SasakiMetal.Hepaticoverexpressionofidolincreasescirculatingproteinconvertasesubtilisin/kexintype9inmiceandhamstersviadualmechanisms:sterolregulatoryelement-bindingprotein2andlow-densitylipoproteinreceptor-dependentpathways.ArteriosclerThrombVascBiol.34,1171-8(2014)(PMID:24675665)
  1. GalabovaGetal.Peptide-basedanti-PCSK9vaccines-anapproachforlong-termLDLcmanagement.PLoSOne.9,e114469(2014)(PMID:25474576)
  1. BergerJMetal.PCSK9-deficiencydoesnotalterbloodpressureandsodiumbalanceinmousemodelsofhypertension.Atherosclerosis239,252-9(2015)(PMID:25621930)
  1. ButkinareeCetal.AmyloidPrecursor-likeProtein2andSortilinDoNotRegulatethePCSK9Convertase-mediatedLowDensityLipoproteinReceptorDegradationbutInteractwithEachOther.JBiolChem.290,18609-20(2015)(PMID:26085104)
  1. AnDetal.IdentificationofPCSK9asanovelserumbioMarkerfortheprenataldiagnosisofneuraltubedefectsusingiTRAQquantitativeproteomics.SciRep.5,17559(2015)(PMID:26691006)
  1. HaasMEetal.TheRoleofProproteinConvertaseSubtilisin/KexinType9inNephroticSyndrome-AssociatedHypercholesterolemia.Circulation134,61-72(2016)(PMID:27358438)
  1. Ngo SockETetal.CombinedEffectsofRosuvastatinandExerciseonGeneExpressionofKeyMoleculesInvolvedinCholesterolMetabolisminOvariectomizedRats.PLoSOne.11,e0159550(2016)(PMID:27442011)
  1. LintnerNGetal.Selectivestallingofhumantranslationthroughsmall-moleculeengagementoftheribosomenascentchain.PLoSBiol.15,e2001882(2017)(PMID:28323820)
  1. XuYXetal.Roleofangiopoietin-like3(ANGPTL3)inregulatingplasmaleveloflow-densitylipoproteincholesterol.Atherosclerosis(2017)Inpress.(PMID:29183623)
Productcategory
Researcharea
Metabolism
Drugdiscovery
品牌介绍
MBL酪氨酸激酶测定试剂盒酪氨酸激酶分为两个主要家族:受体酪氨酸激酶(RTK)和细胞质蛋白(非受体酪氨酸激酶)。受体酪氨酸激酶(RTK)是许多生长因子,细胞因子和激素的高亲和力细胞表面受体。这两个家族在多种细胞信号转导途径中起着至关重要的作用,调节着细胞分裂,粘附,血管生成和存活等多种过程。这些在许多类型的癌症的发生和发展中也起主要作用。CycLex c-Src激酶测定/抑制剂筛选试剂盒旨在测量c-Src重组催化结构域的活性,用于快速,灵敏地评估抑制剂或活化剂。非受体蛋白酪氨酸激酶的Src家族在各种细胞信号转导途径中起着至关重要的作用,调节细胞分裂,运动,粘附,血管生成和存活等各种过程。Src家族激酶的组成型激活变体,包括病毒癌蛋白v-Src和v-Yes,能够诱导多种细胞类型的恶性转化。Src家族激酶,最值得注意的是,尽管并非唯一,但在多种上皮癌和非上皮癌中经常过度表达和/或异常激活。